Furo[3,2‐b]pyridine: A Privileged Scaffold for Highly Selective Kinase Inhibitors and Effective Modulators of the Hedgehog Pathway-Reference-Cited by-同舟云学术

Furo[3,2‐b]pyridine: A Privileged Scaffold for Highly Selective Kinase Inhibitors and Effective Modulators of the Hedgehog Pathway

Published:2019-01-21 Issue:4 Volume:58 Page:1062-1066
ISSN:1433-7851
Container-title:Angewandte Chemie International Edition
language:en
Short-container-title:Angew. Chem. Int. Ed.

Author:

Němec Václav¹²,Hylsová Michaela¹²,Maier Lukáš¹²,Flegel Jana³,Sievers Sonja³,Ziegler Slava³,Schröder Martin⁴,Berger Benedict‐Tilman⁴,Chaikuad Apirat⁴,Valčíková Barbora²⁵,Uldrijan Stjepan²⁵,Drápela Stanislav²⁶,Souček Karel²⁶,Waldmann Herbert³,Knapp Stefan⁴,Paruch Kamil¹²^ORCID

Affiliation:

1. Department of Chemistry, CZ-OpenscreenMasaryk University Kamenice 5 Brno 625 00 Czech Republic

2. International Clinical Research CentreSt. Anne's University Hospital Pekařská 53 Brno 656 91 Czech Republic

3. Max-Planck-Institute für Molekulare PhysiologieAbteilung Chemische Biologie Otto-Hahn-Strasse 11 44227 Dortmund Germany

4. Institute for Pharmaceutical ChemistryStructural Genomics ConsortiumJohann Wolfgang Goethe-University Max-von-Laue-Strasse 15 60438 Frankfurt am Main Germany

5. Department of BiologyFaculty of MedicineMasaryk University Kamenice 5 Brno 625 00 Czech Republic

6. Department of CytokineticsInstitute of Biophysics CAS Královopolská 135 Brno 612 65 Czech Republic

Publisher

Wiley

Subject

General Chemistry,Catalysis

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/anie.201810312

Reference47 articles.

1. 2017/2018 Parexel Biopharmaceutical R&D Statistical Sourcebook PAREXEL International Corporation Waltham 2017.

3. Privileged scaffolds in lead generation

4. Privileged Structures Revisited

5. Privilegierte Strukturen neu betrachtet

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