An Unusual Intramolecular Halogen Bond Guides Conformational Selection-Reference-Cited by-同舟云学术

An Unusual Intramolecular Halogen Bond Guides Conformational Selection

Published:2018-07-09 Issue:31 Volume:57 Page:9970-9975
ISSN:1433-7851
Container-title:Angewandte Chemie International Edition
language:en
Short-container-title:Angew. Chem. Int. Ed.

Author:

Tesch Roberta¹²^ORCID,Becker Christian¹,Müller Matthias Philipp¹^ORCID,Beck Michael Edmund³,Quambusch Lena¹,Getlik Matthäus¹,Lategahn Jonas¹,Uhlenbrock Niklas¹,Costa Fanny Nascimento⁴,Polêto Marcelo D.⁵,Pinheiro Pedro de Sena Murteira²,Rodrigues Daniel Alencar²,Sant'Anna Carlos Mauricio R.²⁶,Ferreira Fabio Furlan⁴,Verli Hugo⁵,Fraga Carlos Alberto Manssour²,Rauh Daniel¹^ORCID

Affiliation:

1. Faculty of Chemistry and Chemical Biology; TU Dortmund University; Otto-Hahn-Strasse 4a 44227 Dortmund Germany

2. Laboratório de Avaliação e Síntese de Substâncias Bioativas (LASSBio), Instituto de Ciências Biomédicas; Universidade Federal do Rio de Janeiro; Av. Carlos Chagas Filho, 373, CEP 21941-902 Rio de Janeiro Brazil

3. Bayer AG; division Crop Science; Alfred-Nobel-Strasse 50 40789 Monheim am Rhein Germany

4. Centro de Ciências Naturais e Humanas; Universidade Federal do ABC; São Paulo Brazil

5. Centro de Biotecnologia; Universidade Federal do Rio Grande do Sul; Av. Bento Gonçalves 9500 Porto Alegre Brazil

6. Departamento de Química; Instituto de Ciências Exatas Universidade Federal Rural do Rio de Janeiro; Seropédica Brazil

Funder

Fundação de Apoio à pesquisa do Rio de Janeiro (FAPERJ)

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Instituto Nacional de Fármacos e Medicamentos (INCT-INOFAR)

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul (FAPERGS)

German Federal Ministry for Education and Research (NGFNPlus and e:Med)

Deutsche Forschungsgemeinschaft (DFG)

European Regional Development Fund: Investing In Your Future

Publisher

Wiley

Subject

General Chemistry,Catalysis

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/anie.201804917/fullpdf

Reference34 articles.

1. Kinase Drug Discovery – What’s Next in the Field?

2. Targeting GSK3 from Ustilago maydis: Type-II Kinase Inhibitors as Potential Antifungals

3. Synthesis and biological evaluation of imidazo[1,2-a]pyridine derivatives as novel PI3 kinase p110α inhibitors

4. Isoform-Selective Inhibition of Phosphoinositide 3-Kinase: Identification of a New Region of Nonconserved Amino Acids Critical for p110α Inhibition

Cited by 14 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Status and Prospects of Molecular Simulations for Drug Discovery;Journal of the Brazilian Chemical Society;2024

2. Glycogen synthase kinase-3: A potential target for diabetes;Bioorganic & Medicinal Chemistry;2023-09

3. Identification of Potential p38γ Inhibitors via In Silico Screening, In Vitro Bioassay and Molecular Dynamics Simulation Studies;International Journal of Molecular Sciences;2023-04-17

4. Mechanisms for the Deactivation of the Electronic Excited States of α-(2-Hydroxyphenyl)-N-phenylnitrone: From Intramolecular Proton and Charge Transfer to Structure Twisting and Aggregation;The Journal of Physical Chemistry B;2022-09-14

5. Glycogen Synthase Kinase 3β Involvement in Neuroinflammation and Neurodegenerative Diseases;Current Medicinal Chemistry;2022-08