High-Throughput Kinetic Analysis for Target-Directed Covalent Ligand Discovery-Reference-Cited by-同舟云学术

High-Throughput Kinetic Analysis for Target-Directed Covalent Ligand Discovery

Published:2018-03-26 Issue:19 Volume:57 Page:5257-5261
ISSN:1433-7851
Container-title:Angewandte Chemie International Edition
language:en
Short-container-title:Angew. Chem. Int. Ed.

Author:

Craven Gregory B.¹²,Affron Dominic P.¹,Allen Charlotte E.¹,Matthies Stefan¹,Greener Joe G.²,Morgan Rhodri M. L.²,Tate Edward W.¹^ORCID,Armstrong Alan¹^ORCID,Mann David J.²^ORCID

Affiliation:

1. Department of Chemistry; Imperial College London; South Kensington Campus London SW7 2AZ UK

2. Department of Life Sciences; Imperial College London; South Kensington Campus London SW7 2AZ UK

Funder

Engineering and Physical Sciences Research Council

Biotechnology and Biological Sciences Research Council

Publisher

Wiley

Subject

General Chemistry,Catalysis

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/anie.201711825/fullpdf

Reference32 articles.

1. Structural Biology and Drug Discovery of Difficult Targets: The Limits of Ligandability

2. Fragment-Based Approaches in Drug Discovery and Chemical Biology

3. Tethering: Fragment-Based Drug Discovery

4. A Small Molecule That Switches a Ubiquitin Ligase From a Processive to a Distributive Enzymatic Mechanism

5. Design of Reversible, Cysteine-Targeted Michael Acceptors Guided by Kinetic and Computational Analysis

Cited by 60 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Recent Development of CDK2 Inhibitors as Anticancer Drugs: An Update (2015–2023);Pharmaceutical Fronts;2024-09-03

2. Advanced technologies for screening and identifying covalent inhibitors;TrAC Trends in Analytical Chemistry;2024-09

3. Inhibitors and PROTACs of CDK2: challenges and opportunities;Expert Opinion on Drug Discovery;2024-07-12

4. Emerging and Re-emerging Warheads for Targeted Covalent Inhibitors: An Update;Journal of Medicinal Chemistry;2024-05-07

5. Covalent hits and where to find them;SLAS Discovery;2024-04