Determinants of the recommended phase 2 dose of molecular targeted agents
Author:
Affiliation:
1. Princess Margaret Cancer Centre; Drug Development Program; Toronto Ontario Canada
2. Institute of Health Policy Management and Evaluation; University of Toronto; Toronto Ontario Canada
Publisher
Wiley
Subject
Cancer Research,Oncology
Reference23 articles.
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3. Clinical benefit in phase-I trials of novel molecularly targeted agents: does dose matter?;Postel-Vinay;Br J Cancer.,2009
4. Dose-response relationship in phase I clinical trials: a European Drug Development Network (EDDN) collaboration study;García;Clin Cancer Res.,2014
5. Meta-analysis of the relationship between dose and benefit in phase I targeted agent trials;Gupta;J Natl Cancer Inst.,2012
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