1. Pharmaceutical Sciences Postgraduate Programme, Pharmacy CourseUniversity of the Itajaí Valley – UNIVALI Itajaí SC 88302‐202 Brazil
2. Department of Pharmaceutical SciencesFederal University of Santa Catarina – UFSC Florianópolis SC 88040‐900 Brazil
3. Laboratory of Research and Development of Drugs. Course of Pharmacy. Pharmaceutical Sciences Postgraduate ProgrammeFederal University of Pampa – UNIPAMPA Uruguaiana RS 97500‐970 Brazil