A Pharmacokinetic Study Comparing Eslicarbazepine Acetate Administered Orally as a Crushed or Intact Tablet in Healthy Volunteers
Author:
Affiliation:
1. Sunovion Pharmaceuticals Inc; Marlborough MA USA
2. Infinity Pharmaceuticals Inc; Cambridge MA USA
3. Quintiles; Overland Park KS USA
Publisher
Wiley
Subject
Pharmacology (medical),Pharmaceutical Science
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/cpdd.242/fullpdf
Reference15 articles.
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2. Eslicarbazepine Acetate
3. Role of eslicarbazepine in the treatment of epilepsy in adult patients with partial-onset seizures;Brown;Ther Clin Risk Manag,2010
4. Development of new antiepileptic drugs: challenges, incentives, and recent advances;Perucca;Lancet Neurol,2007
5. Pharmacokinetics of eslicarbazepine acetate in patients with moderate hepatic impairment;Almeida;Eur J Clin Pharmacol,2008
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2. Papel del acetato de eslicarbazepina en el tratamiento de la epilepsia de origen focal en la edad pediátrica: consideraciones prácticas;Revista de Neurología;2020
3. Modeling and simulations to support dose selection for eslicarbazepine acetate therapy in pediatric patients with partial-onset seizures;Journal of Pharmacokinetics and Pharmacodynamics;2018-06-09
4. Population Pharmacokinetics and Exposure-Response Analyses of Eslicarbazepine Acetate Efficacy and Safety in Monotherapy of Partial-Onset Seizures;The Journal of Clinical Pharmacology;2018-03-12
5. Population Pharmacokinetic Evaluation and Missed-Dose Simulations for Eslicarbazepine Acetate Monotherapy in Patients With Partial-Onset Seizures;Clinical Pharmacology in Drug Development;2017-09-07
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