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Population Pharmacokinetic Evaluation and Missed-Dose Simulations for Eslicarbazepine Acetate Monotherapy in Patients With Partial-Onset Seizures

  • Published:2017-09-07 Issue:3 Volume:7 Page:287-297
  • ISSN:2160-763X
  • Container-title:Clinical Pharmacology in Drug Development
  • language:en
  • Short-container-title:Clinical Pharmacology in Drug Development

Author:

Sunkaraneni Soujanya1,Blum David1,Ludwig Elizabeth2,Chudasama Vaishali2,Fiedler-Kelly Jill2,Marvanova Marketa3,Bainbridge Jacquelyn4,Phillips Luann2

Affiliation:

1. Sunovion Pharmaceuticals Inc; Marlborough MA USA

2. Cognigen Corporation (a SimulationsPlus company ); Buffalo NY USA

3. School of Pharmacy; North Dakota State University; Fargo ND USA

4. Anschutz Medical Campus, University of Colorado; Skaggs School of Pharmacy and Pharmaceutical Sciences; Aurora CO USA

Funder

Sunovion Pharmaceuticals Inc

Publisher

Wiley

Subject

Pharmacology (medical),Pharmaceutical Science

Reference29 articles.

1. Pharmacokinetics and drug interactions of eslicarbazepine acetate;Bialer;Epilepsia,2012

2. Eslicarbazepine Acetate

3. Role of eslicarbazepine in the treatment of epilepsy in adult patients with partial-onset seizures;Brown;Ther Clin Risk Manag,2010

4. Development of new antiepileptic drugs: challenges, incentives, and recent advances;Perucca;Lancet Neurol,2007

5. Pharmacokinetics of eslicarbazepine acetate at steady-state in adults with partial-onset seizures;Perucca;Epilepsy Res,2011

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1. Escitalopram population pharmacokinetics and remedial strategies based on CYP2C19 phenotype;Journal of Affective Disorders;2024-02

2. How drug onset rate and duration of action affect drug forgiveness;Journal of Pharmacokinetics and Pharmacodynamics;2024-01-10

3. Handling Delayed or Missed Dose of Antiseizure Medications;Neurology;2022-11-30

4. Should patients skip late doses of medication? A pharmacokinetic perspective;Journal of Pharmacokinetics and Pharmacodynamics;2022-06-20

5. A pharmacokinetic and pharmacodynamic analysis of drug forgiveness;Journal of Pharmacokinetics and Pharmacodynamics;2022-02-13
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