A genome‐scale metabolic network model and machine learning predict amino acid concentrations in Chinese Hamster Ovary cell cultures-Reference-Cited by-同舟云学术

A genome‐scale metabolic network model and machine learning predict amino acid concentrations in Chinese Hamster Ovary cell cultures

Published:2021-02-19 Issue:5 Volume:118 Page:2118-2123
ISSN:0006-3592
Container-title:Biotechnology and Bioengineering
language:en
Short-container-title:Biotech & Bioengineering

Author:

Schinn Song‐Min¹^ORCID,Morrison Carly²,Wei Wei^ORCID,Zhang Lin²,Lewis Nathan E.¹³⁴^ORCID

Affiliation:

1. Department of Pediatrics University of California San Diego California USA

2. Pfizer, Biotherapeutics Pharmaceutical Sciences Andover Massachusetts USA

3. Department of Bioengineering University of California San Diego California USA

4. Novo Nordisk Foundation Center for Biosustainability at UC San Diego San Diego California USA

Publisher

Wiley

Subject

Applied Microbiology and Biotechnology,Bioengineering,Biotechnology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/bit.27714

Reference26 articles.

1. In-line monitoring of amino acids in mammalian cell cultures using raman spectroscopy and multivariate chemometrics models

2. Application of a curated genome-scale metabolic model of CHO DG44 to an industrial fed-batch process

3. An unconventional uptake rate objective function approach enhances applicability of genome‐scale models for mammalian cells;Chen Y.;NPJ Systems Biology and Applications,2019

4. Metabolic responses of CHO cells to limitation of key amino acids

5. COBRApy: COnstraints-Based Reconstruction and Analysis for Python

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