Affiliation:
1. Novartis Pharma AG Novartis Campus CH-4056 Basel Switzerland
Abstract
AbstractA scalable and environmentally benign protocol for a Suzuki–Miyaura cross‐coupling in water using vitamin E derived surfactant TPGS‐750‐M is reported. The protocol is the most simple and standard for such transformations under micellar catalysis that has been amply utilized within our own research and development portfolio over the last decade. The impact of the synthetic procedure is reenforced by green Process Mass Intensity and Total Carbon Release metrics.
Subject
Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Drug Discovery,Biochemistry,Catalysis
Cited by
2 articles.
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