Genome‐wide association and multi‐omics studies identify <i>MGMT</i> as a novel risk gene for Alzheimer's disease among women-Reference-Cited by-同舟云学术

Genome‐wide association and multi‐omics studies identify MGMT as a novel risk gene for Alzheimer's disease among women

Published:2022-06-30 Issue:3 Volume:19 Page:896-908
ISSN:1552-5260
Container-title:Alzheimer's & Dementia
language:en
Short-container-title:Alzheimer's & Dementia

Author:

Chung Jaeyoon¹,Das Anjali²,Sun Xinyu¹,Sobreira Débora R.³,Leung Yuk Yee⁴,Igartua Catherine²,Mozaffari Sahar²,Chou Yi‐Fan⁴,Thiagalingam Sam¹,Mez Jesse⁵,Zhang Xiaoling¹,Jun Gyungah R.¹⁶⁷,Stein Thor D.⁸,Kunkle Brian W.⁹,Martin Eden R.⁹,Pericak‐Vance Margaret A.⁹,Mayeux Richard¹⁰,Haines Jonathan L.¹¹,Schellenberg Gerard D.⁴,Nobrega Marcelo A.²,Lunetta Kathryn L.⁷,Pinto Jayant M.³,Wang Li‐San⁴,Ober Carole²,Farrer Lindsay A.¹⁵⁶⁷¹²

Affiliation:

1. Department of Medicine (Biomedical Genetics) Boston University School of Medicine Boston Massachusetts USA

2. Department of Human Genetics The University of Chicago Chicago Illinois USA

3. Department of Surgery/Section of Otolaryngology‐Head and Neck Surgery The University of Chicago Chicago Illinois USA

4. Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine University of Pennsylvania Perelman School of Medicine Philadelphia Pennsylvania USA

5. Department of Neurology Boston University School of Medicine Boston Massachusetts USA

6. Department of Ophthalmology Boston University School of Medicine Boston Massachusetts USA

7. Department of Biostatistics Boston University School of Public Health Boston Massachusetts USA

8. Department of Pathology & Laboratory Medicine Boston University School of Medicine Boston Massachusetts USA

9. Dr. John T. Macdonald Foundation of Human Genetics and John P. Hussman Institute for Human Genomics University of Miami Miller School of Medicine Miami Florida USA

10. Department of Neurology Columbia University New York City New York USA

11. Department of Population and Quantitative Health Sciences and Cleveland Institute for Computational Biology Case Western Reserve University Cleveland Ohio USA

12. Department of Epidemiology Boston University School of Public Health Boston Massachusetts USA

Publisher

Wiley

Subject

Psychiatry and Mental health,Cellular and Molecular Neuroscience,Geriatrics and Gerontology,Neurology (clinical),Developmental Neuroscience,Health Policy,Epidemiology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/alz.12719

Reference49 articles.

1. 2021 Alzheimer's disease facts and figures

2. Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy

3. New insights into the genetic etiology of Alzheimer’s disease and related dementias

4. Finding the missing heritability of complex diseases

5. A novel Alzheimer disease locus located near the gene encoding tau protein

Cited by 27 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. GDC: An Integrated Resource to Explore the Pathogenesis of Hearing Loss through Genetics and Genomics;2024-08-20

2. MADDD-seq, a novel massively parallel sequencing tool for simultaneous detection of DNA damage and mutations;Nucleic Acids Research;2024-08-16

3. Toward the development of a sporadic model of Alzheimer's disease: comparing pathologies between humanized APP and the familial J20 mouse models;Frontiers in Aging Neuroscience;2024-07-08

4. Brain high-throughput multi-omics data reveal molecular heterogeneity in Alzheimer’s disease;PLOS Biology;2024-04-30

5. Multiple checkpoints ensure ribosomes have the correct end;PLOS Biology;2024-04-30