Pharmacokinetics and Safety of the Selective Progesterone Receptor Modulator Vilaprisan in Chinese Healthy Postmenopausal Women-Reference-Cited by-同舟云学术

Pharmacokinetics and Safety of the Selective Progesterone Receptor Modulator Vilaprisan in Chinese Healthy Postmenopausal Women

Published:2020-07-27 Issue:5 Volume:10 Page:486-493
ISSN:2160-763X
Container-title:Clinical Pharmacology in Drug Development
language:en
Short-container-title:Clinical Pharmacology in Drug Development

Author:

Liu Hongzhong¹,Jiang Ji¹,Chen Zhaozhao²,Zhang Yunhui²,Li Jinyi²,Hoechel Joachim²,Rohde Beate²,Zimmermann Torsten²,Schultze‐Mosgau Marcus‐Hillert²

Affiliation:

1. Clinical Pharmacology Research Center Peking Union Medical College Hospital Chinese Academy of Medical Sciences & Peking Union Medical College Beijing Key Laboratory of Clinical PK & PD Investigation for Innovative Drugs Beijing China

2. Bayer AG, Clinical Pharmacology Berlin Germany

Funder

Bayer

Publisher

Wiley

Subject

Pharmacology (medical),Pharmaceutical Science

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cpdd.851

Reference20 articles.

1. Investigational developments for the treatment of progesterone-dependent diseases

2. A Novel Selective Progesterone Receptor Modulator Asoprisnil (J867) Inhibits Proliferation and Induces Apoptosis in Cultured Human Uterine Leiomyoma Cells in the Absence of Comparable Effects on Myometrial Cells

3. Effect of a Selective Progesterone Receptor Modulator on Induction of Apoptosis in Uterine Fibroids In Vivo

4. BAY 1002670: a novel, highly potent and selective progesterone receptor modulator for gynaecological therapies

5. Pharmacodynamics and safety of the novel selective progesterone receptor modulator vilaprisan: a double-blind, randomized, placebo-controlled phase 1 trial in healthy women

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1. Systematic review of oral pharmacotherapeutic options for the management of uterine fibroids;Journal of the American Pharmacists Association;2022-05

2. Single- and Multiple-Dose Pharmacokinetics and Safety of Vilaprisan in Healthy Postmenopausal Japanese Women: A Randomized Clinical Trial;European Journal of Drug Metabolism and Pharmacokinetics;2021-10-11

3. Clinical Pharmacokinetics and Pharmacodynamics of the Selective Progesterone Receptor Modulator Vilaprisan: A Comprehensive Overview;Clinical Pharmacokinetics;2021-09-27

4. Effect of Food Intake on the Pharmacokinetics of the Selective Progesterone Receptor Modulator Vilaprisan: A Randomized Clinical Study in Healthy Postmenopausal Women;Clinical Pharmacology in Drug Development;2020-10-05