Effective childhood cancer treatment: The impact of large scale clinical trials in Germany and Austria

Author:

Rossig C.1,Juergens H.1,Schrappe M.2,Moericke A.2,Henze G.3,von Stackelberg A.3,Reinhardt D.4,Burkhardt B.15,Woessmann W.5,Zimmermann M.4,Gadner H.6,Mann G.7,Schellong G.1,Mauz-Koerholz C.8,Dirksen U.1,Bielack S.9,Berthold F.10,Graf N.11,Rutkowski S.12,Calaminus G.1,Kaatsch P.13,Creutzig U.14

Affiliation:

1. Pediatric Hematology and Oncology; University Children's Hospital Muenster; Muenster Germany

2. Department of Pediatrics; University Medical Center Schleswig-Holstein; Campus Kiel Kiel Germany

3. Department of Pediatric Oncology/Hematology; Charité Universitätsmedizin Berlin; Berlin Germany

4. Pediatric Hematology and Oncology; Hannover Medical High School; Hannover Germany

5. Department of Pediatric Hematology and Oncology; Justus-Liebig-University; Giessen Germany

6. St. Anna Children's Cancer Research Institute; Department of Pediatrics; Medical University School; Vienna Austria

7. St. Anna Children's Hospital; Department of Pediatrics; Medical University School; Vienna Austria

8. Department of Paediatrics; Martin-Luther University of Halle-Wittenberg; Halle Germany

9. Klinikum Stuttgart-Olgahospital; Pediatrics 5 (Oncology, Hematology, Immunology; General Pediatrics, Gastroenterology, Rheumatology); Stuttgart Germany

10. Department of Pediatric Oncology and Hematology; Children's Hospital; University of Cologne; Cologne Germany

11. Pediatric Oncology; University Hospital of Saarland; Homburg/Saar Germany

12. Department of Pediatric Hematology and Oncology; University Medical Center Hamburg-Eppendorf; Hamburg Germany

13. German Childhood Cancer Registry at Institute for Medical Biostatistics, Epidemiology and Informatics; University Medical Center of Johannes Gutenberg-University; Mainz Germany

Funder

Roche und Pfizer

Publisher

Wiley

Subject

Oncology,Hematology,Pediatrics, Perinatology, and Child Health

Reference98 articles.

1. Quality, comparability, methods of analysis of data on childhood cancer in Europe, (1978-1997): Report from the ACCIS project;Steliarova-Foucher;Eur J Cancer,2006

2. Kaatsch P Spix J www.kinderkrebsregister.de

3. A study of “total therapy” of acute lymphocytic leukemia in children;George;J Pediatr,1968

4. Results of Memphis-study VII (“Pinkel-Therapy”) in 659 children with acute lymphoblastic leukemia. Cooperative therapeutic study of the F German working group on childhood leukemia with participation of 42 hospitals;Lampert;Klin Padiatr,1978

5. ALL therapy study, 1971-1974 of the German working group for leukemia research and therapy in childhood: Prognostic significance of initial features and different therapeutic modalities;Henze;Klin Padiatr,1979

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