Characterization of <scp>TR</scp> ‐107, a novel chemical activator of the human mitochondrial protease <scp>ClpP</scp>-Reference-Cited by-同舟云学术

Characterization of TR ‐107, a novel chemical activator of the human mitochondrial protease ClpP

Published:2022-08 Issue:4 Volume:10 Page:
ISSN:2052-1707
Container-title:Pharmacology Research & Perspectives
language:en
Short-container-title:Pharmacology Res & Perspec

Author:

Fennell Emily M. J.¹,Aponte‐Collazo Lucas J.¹,Wynn Joshua D.¹,Drizyte‐Miller Kristina¹,Leung Elisa²,Greer Yoshimi Endo³,Graves Paul R.⁴,Iwanowicz Andrew A.⁵,Ashamalla Hani⁴,Holmuhamedov Ekhson⁶,Lang Henk⁵,Karanewsky Donald S.⁵,Der Channing J.¹,Houry Walid A.²⁷,Lipkowitz Stanley³,Iwanowicz Edwin J.⁵,Graves Lee M.¹^ORCID

Affiliation:

1. Department of Pharmacology and the Lineberger Comprehensive Cancer Center University of North Carolina at Chapel Hill Chapel Hill North Carolina USA

2. Department of Biochemistry University of Toronto Toronto Ontario Canada

3. Women's Malignancies Branch Center for Cancer Research, National Cancer Institute, National Institutes of Health Bethesda Maryland USA

4. Department of Radiation Oncology New York Presbyterian Brooklyn Methodist Hospital Brooklyn New York USA

5. Madera Therapeutics LLC Chapel Hill North Carolina USA

6. Institute of Theoretical and Experimental Biophysics Russian Academy of Sciences Pushchino Russian Federation

7. Department of Chemistry University of Toronto Toronto Ontario Canada

Funder

Canadian Cancer Society Research Institute

Canadian Institutes of Health Research

National Institutes of Health

Publisher

Wiley