The rs429358 Locus in Apolipoprotein E Is Associated With Hepatocellular Carcinoma in Patients With Cirrhosis

Author:

Innes Hamish123,Nischalke Hans Dieter4,Guha Indra Neil5ORCID,Weiss Karl Heinz6,Irving Will5,Gotthardt Daniel7,Barnes Eleanor8,Fischer Janett9,Ansari M. Azim8,Rosendahl Jonas10,Lin Shang‐Kuan8,Marot Astrid1112,Pedergnana Vincent13,Casper Markus14,Benselin Jennifer5,Lammert Frank14,McLauchlan John15,Lutz Philip L.4ORCID,Hamill Victoria13,Mueller Sebastian1617,Morling Joanne R.25,Semmler Georg1819ORCID,Eyer Florian20ORCID,von Felden Johann21ORCID,Link Alexander22,Vogel Arndt23,Marquardt Jens U.24ORCID,Sulk Stefan25,Trebicka Jonel2627ORCID,Valenti Luca2829ORCID,Datz Christian19ORCID,Reiberger Thomas18ORCID,Schafmayer Clemens30,Berg Thomas9,Deltenre Pierre113132ORCID,Hampe Jochen2533,Stickel Felix34,Buch Stephan25

Affiliation:

1. School of Health and Life Sciences Glasgow Caledonian University Glasgow United Kingdom

2. Population and Lifespan Sciences School of Medicine University of Nottingham Nottingham United Kingdom

3. Public Health Scotland Glasgow United Kingdom

4. Department of Internal Medicine I University HospitalUniversity of Bonn Bonn Germany

5. National Institute for Health Research (NIHR), Nottingham Biomedical Research Centre Nottingham University Hospitals National Health Service Trust and the University of Nottingham Nottingham United Kingdom

6. Department of Gastroenterology and Hepatology University Hospital Heidelberg Heidelberg Germany

7. Department of Internal Medicine IV Medical University of Heidelberg Heidelberg Germany

8. Peter Medawar Building for Pathogen Research Nuffield Department of Medicine and the Oxford NIHR Biomedical Research Centre Oxford University Oxford United Kingdom

9. Division of Hepatology Department of Medicine II Laboratory for Clinical and Experimental Hepatology Leipzig University Medical Center Leipzig Germany

10. Medical Department 1 University Hospital HalleMartin‐Luther Universität Halle‐Wittenberg Halle Germany

11. Division of Gastroenterology and Hepatology Centre Hospitalier Universitaire VaudoisUniversité de Lausanne Lausanne Switzerland

12. Department of Gastroenterology and Hepatology Centre Hospitalier UniversitaireUCLouvain NamurUniversité Catholique de Louvain Yvoir Belgium

13. Laboratoire MIVEGEC Montpellier France

14. Department of Medicine II Saarland University Medical CenterSaarland University Homburg Germany

15. Medical Research Council‐University of Glasgow Centre for Virus Research Glasgow United Kingdom

16. Center for Alcohol Research University of Heidelberg Heidelberg Germany

17. Medical Department Salem Medical Center Heidelberg Germany

18. Department of Internal Medicine III Division of Gastroenterology and Hepatology Medical University of Vienna Vienna Austria

19. Department of Internal Medicine, General Hospital Oberndorf, Teaching Hospital of the Paracelsus Medical University Salzburg Oberndorf Austria

20. Department of Clinical Toxicology Klinikum Rechts der Isar Technical University of Munich Munich Germany

21. Department of Medicine University Medical Center Hamburg‐Eppendorf Hamburg Germany

22. Department of Gastroenterology, Hepatology, and Infectious Diseases Otto‐von‐Guericke University Hospital Magdeburg Germany

23. Department of Gastroenterology, Hepatology, and Endocrinology Hannover Medical School Hannover Germany

24. Department of Medicine I University Hospital Schleswig Holstein–Campus Lübeck Lübeck Germany

25. Medical Department 1 University Hospital DresdenTechnische Universität Dresden Dresden Germany

26. Department of Internal Medicine I Goethe University Frankfurt Germany

27. European Foundation for Study of Chronic Liver Failure Barcelona Spain

28. Precision Medicine–Department of Transfusion Medicine and Hematology Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico Milan Italy

29. Department of Pathophysiology and Transplantation Università degli Studi di Milano Milan Italy

30. Department of General, Visceral, Vascular, and Transplant Surgery Rostock University Medical Center Rostock Germany

31. Department of Gastroenterology Hepatopancreatology, and Digestive Oncology University Clinics of Brussels Hospital Erasme Brussels Belgium

32. Department of Gastroenterology and Hepatology Clinique St Luc Bouge Belgium

33. Center for Regenerative Therapies Dresden Technische Universität Dresden Dresden Germany

34. Department of Gastroenterology and Hepatology University Hospital of Zurich Zurich Switzerland

Funder

Medical Research Council

Cancer Research UK

Swiss Foundation for Alcohol Research

Publisher

Wiley

Subject

Hepatology

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