Use of a Removable Backbone Modification Strategy to Prevent Aspartimide Formation in the Synthesis of Asp Lactam Cyclic Peptides †-Reference-Cited by-同舟云学术

Use of a Removable Backbone Modification Strategy to Prevent Aspartimide Formation in the Synthesis of Asp Lactam Cyclic Peptides †

Published:2021-07-26 Issue:9 Volume:39 Page:2517-2522
ISSN:1001-604X
Container-title:Chinese Journal of Chemistry
language:en
Short-container-title:Chin. J. Chem.

Author:

Cui Tingting¹,Chen Junyou¹,Zhao Rui²,Guo Yanyan¹,Tang Jiahui¹,Li Yulei³,Li Yi‐Ming¹,Bierer Donald⁴,Liu Lei³

Affiliation:

1. School of Food and Biological Engineering, Engineering Research Center of Bio‐process, Ministry of Education Hefei University of Technology Hefei Anhui 230009 China

2. Department of Chemistry University of Science and Technology of China Hefei Anhui 230026 China

3. Tsinghua‐Peking Center for Life Sciences, Ministry of Education Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology, Center for Synthetic and Systems Biology, Department of Chemistry Tsinghua University Beijing 100084 China

4. Department of Medicinal Chemistry, Bayer AG, Aprather Weg 18A, 42096 Wuppertal Germany

Publisher

Wiley

Subject

General Chemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cjoc.202100272

Reference36 articles.

1. Development of Potent Glucagon-like Peptide-1 Agonists with High Enzyme Stability via Introduction of Multiple Lactam Bridges

2. The synthesis and study of side-chain lactam-bridged peptides

3. Bis‐Lactam Peptide [ i , i + 4]‐Stapling

4. Targeting SARS-CoV-2 spike protein by stapled hACE2 peptides

5. Peptideo-Aminoanilides as Crypto-Thioesters for Protein Chemical Synthesis

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