Development of Potent Glucagon-like Peptide-1 Agonists with High Enzyme Stability via Introduction of Multiple Lactam Bridges
Author:
Affiliation:
1. Department of Chemistry, University of Texas at Dallas, Richardson, Texas 75080
2. Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15260
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm100602m
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2. The entero-insular axis in type 2 diabetes - incretins as therapeutic agents
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4. Receptors for glucagon-like peptide-1(7–36) amide on rat insulinoma-derived cells
5. Truncated glucagon-like peptide I, an insulin-releasing hormone from the distal gut
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