Concise Review: The Use of Adipose-Derived Stromal Vascular Fraction Cells and Platelet Rich Plasma in Regenerative Plastic Surgery

Author:

Gentile Pietro12,Scioli Maria Giovanna3,Bielli Alessandra3,Orlandi Augusto3,Cervelli Valerio1

Affiliation:

1. a Plastic and Reconstructive Surgery, University of Rome “Tor Vergata”, Rome, Italy

2. b Plastic and Reconstructive Surgery, Catholic University “Our Lady of Good Counsel”, Tirane, Albania

3. c Anatomic Pathology Institute, University of Rome “Tor Vergata”, Rome, Italy

Abstract

Abstract Tissue engineering has emerged at the intersection of numerous disciplines to meet a global clinical need for technologies to promote the regeneration of tissues. Recently, many authors have focused their attention on mesenchymal stem/stromal cells (MSCs) for their capacity to differentiate into many cell lineages. The most widely studied cell types are bone marrow mesenchymal stem cells and adipose-derived stem cells (ASCs), which display similar results. Biomaterials, cells, and growth factors are needed to design a regenerative plastic surgery approach in the treatment of organ and tissue defects, but not all tissues are created equal. The aim of this article is to describe the advances in tissue engineering through the use of ASCs, platelet rich plasma, and biomaterials to enable regeneration of damaged complex tissue.

Publisher

Oxford University Press (OUP)

Subject

Cell Biology,Developmental Biology,Molecular Medicine

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