Population Pharmacokinetics and Exposure‐Response Relationship of Luspatercept, an Erythroid Maturation Agent, in Anemic Patients With β‐Thalassemia
Author:
Affiliation:
1. Bristol Myers Squibb Princeton New Jersey USA
2. Certara Strategic Consulting Princeton New Jersey USA
3. Celgene International A Bristol‐Meyers Squibb Company Boudry Switzerland
4. Acceleron Pharma Cambridge Massachusetts USA
Funder
Bristol-Myers Squibb
Publisher
Wiley
Subject
Pharmacology (medical),Pharmacology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/jcph.1696
Reference11 articles.
1. β-Thalassemia
2. Thalassaemia
3. TGFβ–SMAD signal transduction: molecular specificity and functional flexibility
4. Modified activin receptor IIB ligand trap mitigates ineffective erythropoiesis and disease complications in murine β-thalassemia
5. Transforming growth factor-β superfamily ligand trap ACE-536 corrects anemia by promoting late-stage erythropoiesis
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1. Management of luspatercept therapy in patients with transfusion‐dependent β‐thalassaemia;British Journal of Haematology;2023-04-10
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