In vivo evidence for pre-symptomatic neuroinflammation in a MAPT mutation carrier

Author:

Bevan-Jones W. Richard1,Cope Thomas E.2,Jones P. Simon2,Passamonti Luca2,Hong Young T.3,Fryer Tim3,Arnold Robert1,Coles Jonathan P.4,Aigbirhio Franklin I.3,O'Brien John T.1,Rowe James B.25

Affiliation:

1. Department of Psychiatry; University of Cambridge; Cambridge United Kingdom

2. Department of Clinical Neurosciences; University of Cambridge; Cambridge United Kingdom

3. Wolfson Brain Imaging Centre; University of Cambridge; Cambridge United Kingdom

4. Division of Anaesthesia; University of Cambridge; Cambridge United Kingdom

5. Medical Research Council Cognition and Brain Sciences Unit; Cambridge United Kingdom

Funder

National Institute for Health Research

Wellcome Trust

Patrick Berthoud Charitable Trust

the Association of British Neurologists

Publisher

Wiley

Subject

Clinical Neurology,General Neuroscience

Reference27 articles.

1. Frontotemporal dementia;Bang;Lancet,2015

2. Rest in peace FTDP-17;Josephs;Brain,2018

3. Retiring the term FTDP-17 as MAPT mutations are genetic forms of sporadic frontotemporal tauopathies;Forrest;Brain a J Neurol a J Neurol,2018

4. Presymptomatic cognitive and neuroanatomical changes in genetic frontotemporal dementia in the Genetic Frontotemporal dementia Initiative (GENFI) study: a cross-sectional analysis;Rohrer;Lancet Neurol,2015

5. Patterns of gray matter atrophy in genetic frontotemporal dementia : results from the GENFI study;Cash;Neurobiology,2018

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