Limitations of clinical trial sample size estimate by subtraction of two measurements

Author:

Chen Kewei1234ORCID,Guo Xiaojuan45,Pan Rong2ORCID,Xiong Chengjie67,Harvey Danielle J.8,Chen Yinghua19,Yao Li4,Su Yi14,Reiman Eric M.191011,

Affiliation:

1. Banner Alzheimer's Institute Phoenix Arizona USA

2. Department of Mathematics and Statistics Arizona State University Tempe Arizona USA

3. Department of Neurology University of Arizona Phoenix Arizona USA

4. Arizona Alzheimer's Consortium Phoenix Arizona USA

5. School of Artificial Intelligence Beijing Normal University Beijing China

6. Beijing Key Laboratory of Brain Imaging and Connectomics Beijing Normal University Beijing China

7. Knight Alzheimer's Disease Research Center St. Louis Missouri USA

8. Division of Biostatistics Washington University School of Medicine in St. Louis St. Louis Missouri USA

9. Department of Public Health and Sciences University of California Davis California USA

10. Division of Neurogenomics Translational Genomics Research Institute Phoenix Arizona USA

11. Department of Psychiatry University of Arizona Tucson Arizona USA

Funder

National Institute of Mental Health

National Institute on Aging

National Natural Science Foundation of China

National Science Foundation of Sri Lanka

Publisher

Wiley

Subject

Statistics and Probability,Epidemiology

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