The serotonin receptor 2A (HTR2A) rs6313 variant is associated with higher ongoing pain and signs of central sensitization in neuropathic pain patients-Reference-Cited by-同舟云学术

The serotonin receptor 2A (HTR2A) rs6313 variant is associated with higher ongoing pain and signs of central sensitization in neuropathic pain patients

Published:2020-12-03 Issue:3 Volume:25 Page:595-611
ISSN:1090-3801
Container-title:European Journal of Pain
language:en
Short-container-title:Eur. J. Pain

Author:

Sachau Juliane¹,Bruckmueller Henrike²³,Gierthmühlen Janne¹,Magerl Walter⁴,May Denisa²,Binder Andreas¹,Forstenpointner Julia¹,Koetting Judith⁵,Maier Christoph⁶,Tölle Thomas R.⁷,Treede Rolf‐Detlef⁴,Berthele Achim⁷,Caliebe Amke⁸,Diesch Carolin²,Flor Herta⁹,Huge Volker¹⁰,Maihöfner Christian¹¹,Rehm Stefanie¹,Kersebaum Dilara¹,Fabig Sophie‐Charlotte¹,Vollert Jan⁴¹²,Rolke Roman¹³,Stemmler Susanne⁵,Sommer Claudia¹⁴,Westermann Andrea⁶,Cascorbi Ingolf²,Baron Ralf¹

Affiliation:

1. Division of Neurological Pain Research and Therapy Department of Neurology University Hospital Schleswig‐Holstein, Campus Kiel Kiel Germany

2. Institute of Experimental and Clinical Pharmacology University Hospital Schleswig‐Holstein, Campus Kiel Kiel Germany

3. Department of Pharmacy UiT The Arctic University of Norway Tromsø Norway

4. Chair of Neurophysiology Mannheim Center for Translational Neuroscience Ruprecht Karls University Heidelberg Mannheim Germany

5. Department of Human Genetics Ruhr University Bochum Bochum Germany

6. Department of Pain Management BG Kliniken BergmannsheilRuhr University Bochum Bochum Germany

7. Department of Neurology Klinikum Rechts der IsarTechnical University Munich München Germany

8. Institute of Medical Informatics and Statistics Christian‐Albrechts‐University and University Hospital Schleswig‐Holstein Kiel Germany

9. Department of Clinical and Cognitive Neuroscience Central Institute for Mental Health Medical Faculty Mannheim Ruprecht Karls University Heidelberg Mannheim Germany

10. Department of Anaesthesiology Ludwig Maximilians University Munich München Germany

11. Department of Neurology General Hospital FürthUniversity of Erlangen‐Nuremberg Nuremberg Germany

12. Pain Research Department of Surgery and Cancer Imperial College London London UK

13. Department of Palliative Medicine Medical Faculty RWTH Aachen University Aachen Germany

14. Department of Neurology University of Würzburg Würzburg Germany

Publisher

Wiley

Subject

Anesthesiology and Pain Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ejp.1696

Reference58 articles.

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2. 5-HT2A Receptor-Induced Morphological Reorganization of PKCγ-Expressing Interneurons Gates Inflammatory Mechanical Allodynia in Rat

3. Association between 5-hydroxytryptamine 2A receptor gene polymorphism and postoperative analgesic requirements after major abdominal surgery

4. PKCγ interneurons, a gateway to pathological pain in the dorsal horn

5. Neuropathic pain: diagnosis, pathophysiological mechanisms, and treatment

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