Structural Basis of Sirtuin 6 Activation by Synthetic Small Molecules-Reference-Cited by-同舟云学术

Structural Basis of Sirtuin 6 Activation by Synthetic Small Molecules

Published:2016-12-19 Issue:4 Volume:129 Page:1027-1031
ISSN:0044-8249
Container-title:Angewandte Chemie
language:en
Short-container-title:Angew. Chem.

Author:

You Weijie¹,Rotili Dante²,Li Tie-Mei³⁴,Kambach Christian¹,Meleshin Marat⁵,Schutkowski Mike⁵,Chua Katrin F.³⁴,Mai Antonello²,Steegborn Clemens¹

Affiliation:

1. Universität Bayreuth; Lehrstuhl Biochemie und Forschungszentrum für Biomakromoleküle; Universitätsstr. 30 95447 Bayreuth Germany

2. Sapienza University Roma; Department of Drug Chemistry and Technologies and Pasteur Institute of the Cenci-Bolognetti Foundation; P. le A. Moro 5 00185 Rome Italy

3. Department of Medicine; Stanford University School of Medicine; 300 Pasteur Drive Grant Bldg., Rm. S-025 Stanford CA 94305 USA

4. Geriatric Research, Education, and Clinical Center; Department of Veterans Affairs Palo Alto Health Care System; Palo Alto CA 94304 USA

5. Abteilung Enzymology; Institut für Biochemie und Biotechnologie; Martin-Luther-Universität; Kurt-Mothes-Str. 3 06110 Halle (Saale) Germany

Publisher

Wiley

Subject

General Medicine

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/ange.201610082/fullpdf

Reference22 articles.

1. Seven sirtuins for seven deadly diseases ofaging

2. Small molecule SIRT1 activators for the treatment of aging and age-related diseases

3. Using mitochondrial sirtuins as drug targets: disease implications and available compounds

4. New assays and approaches for discovery and design of Sirtuin modulators

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