Artemisinin–(Iso)quinoline Hybrids by C−H Activation and Click Chemistry: Combating Multidrug‐Resistant Malaria

Author:

Çapcı Aysun1,Lorion Mélanie M.2ORCID,Wang Hui2ORCID,Simon Nina3ORCID,Leidenberger Maria3,Borges Silva Mariana C.4,Moreira Diogo R. M.4ORCID,Zhu Yongping5,Meng Yuqing5,Chen Jia Yun5,Lee Yew Mun6,Friedrich Oliver3ORCID,Kappes Barbara3,Wang Jigang57ORCID,Ackermann Lutz28ORCID,Tsogoeva Svetlana B.1ORCID

Affiliation:

1. Organic Chemistry Chair I and Interdisciplinary Center for Molecular Materials (ICMM) Friedrich-Alexander University of Erlangen-Nürnberg Nikolaus-Fiebiger-Straße 10 91054 Erlangen Germany

2. Institut für Organische und Biomolekulare Chemie Georg-August-Universität Göttingen Tammannstraße 2 37077 Göttingen Germany

3. Institute of Medical Biotechnology Friedrich-Alexander University of Erlangen-Nürnberg Paul-Gordon-Straße 3 91052 Erlangen Germany

4. Fiocruz, Instituto Gonçalo Moniz, 40296-710 Salvador, BA Brazil

5. Artemisinin Research Center, and Institute of Chinese Materia Medica China Academy of Chinese Medical Sciences Beijing 100700 China

6. Department of Biological Sciences National University of Singapore 117600 Singapore Singapore

7. Shenzhen People's Hospital Shenzhen 518020 China

8. German Center for Cardiovascular Research (DZHK) Germany

Funder

Deutsche Forschungsgemeinschaft

Alexander von Humboldt-Stiftung

Fundação de Amparo à Pesquisa do Estado da Bahia

Deutscher Akademischer Austauschdienst

Innovative Research Group Project of the National Natural Science Foundation of China

Publisher

Wiley

Subject

General Medicine

Reference64 articles.

1. World Health Organization (2018) World Malaria Report 2018;http://www.who.int/iris/handle/10665/275867. License: CC BY-NC-SA 3.0 IGO.

2. Quinolines and Artemisinin: Chemistry, Biology and History

3.  

4. The discovery of artemisinin (qinghaosu) and gifts from Chinese medicine

5. Artemisinin-A Gift from Traditional Chinese Medicine to the World (Nobel Lecture)

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