Lösung des Problems mangelnder oraler Verfügbarkeit cyclischer Hexapeptide: Entwicklung eines selektiven, oral verfügbaren Liganden für das Integrin αvβ3-Reference-Cited by-同舟云学术

Lösung des Problems mangelnder oraler Verfügbarkeit cyclischer Hexapeptide: Entwicklung eines selektiven, oral verfügbaren Liganden für das Integrin αvβ3

Published:2017-11-23 Issue:51 Volume:129 Page:16624-16629
ISSN:0044-8249
Container-title:Angewandte Chemie
language:en
Short-container-title:Angew. Chem.

Author:

Weinmüller Michael¹,Rechenmacher Florian¹,Kiran Marelli Udaya²,Reichart Florian¹,Kapp Tobias G.¹,Räder Andreas F. B.¹,Di Leva Francesco Saverio³,Marinelli Luciana³,Novellino Ettore³,Muñoz-Félix José M.⁴,Hodivala-Dilke Kairbaan⁴,Schumacher Adi⁵,Fanous Joseph⁵,Gilon Chaim⁵,Hoffman Amnon⁵,Kessler Horst¹^ORCID

Affiliation:

1. Institute for Advanced Study und Center of Integrated Protein, Science; Department Chemie; Technische Universität München; Lichtenbergstraße 4 85748 Garching Deutschland

2. Central NMR Facility and Division of Organic Chemistry; CSIR-National Chemical Laboratory; Pune Indien

3. Dipartimento di Farmacia; Università di Napoli Federico II; Italien

4. Centre for Tumour Biology; Barts Cancer Institute, -; Queen Mary University of London; John Vane Science Centre; Großbritannien

5. Institutes of Chemistry and Drug Research; The Hebrew University of Jerusalem; Israel

Funder

Deutsche Forschungsgemeinschaft

Worldwide Cancer Research

Cancer Research UK

MIUR-PRIN 2015

Publisher

Wiley

Subject

General Medicine

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/ange.201709709/fullpdf

Reference30 articles.

1. Cell attachment activity of fibronectin can be duplicated by small synthetic fragments of the molecule

2. Arg-Gly-Asp constrained within cyclic pentapoptides Strong and selective inhibitors of cell adhesion to vitronectin and laminin fragment P1

3. Stereoisomeric Peptide Libraries and Peptidomimetics for Designing Selective Inhibitors of theαvβ3 Integrin for a New Cancer Therapy

4. Stereoisomere Peptid-Bibliotheken und Peptidmimetika zum Design von selektiven Inhibitoren des αv β3-Integrins für eine neuartige Krebstherapie

5. N-Methylated Cyclic RGD Peptides as Highly Active and Selective αVβ3 Integrin Antagonists

Cited by 5 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Piptides: New, Easily Accessible Chemotypes For Interactions With Biomolecules;Angewandte Chemie International Edition;2021-02-04

2. Piptides: New, Easily Accessible Chemotypes For Interactions With Biomolecules;Angewandte Chemie;2021-02-04

3. Bioconjugation of Supramolecular Metallacages to Integrin Ligands for Targeted Delivery of Cisplatin;Bioconjugate Chemistry;2018-10-31

4. Orally Active Peptides: Is There a Magic Bullet?;Angewandte Chemie International Edition;2018-10-03

5. Oral aktive Peptide: Gibt es ein Patentrezept?;Angewandte Chemie;2018-10-03