Modeling of substrate elimination by the liver: Has the albumin receptor model superseded the well-stirred model?
Author:
Publisher
Wiley
Subject
Hepatology
Reference60 articles.
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1. Optimal experimental design for precise estimation of the parameters of the axial dispersion model of hepatic elimination;Journal of Pharmacokinetics and Pharmacodynamics;1998
2. Modeling of drug elimination by the liver. 1. Main concepts and physiologically justified clearance models (a review);Pharmaceutical Chemistry Journal;1996-05
3. Kinetics of Bilirubin Transfer between Serum Albumin and Membrane Vesicles;Journal of Biological Chemistry;1995-01
4. Pharmacokinetic modeling of the elimination of drugs by the liver. II. Influence of the localization and activity of metabolizing enzymes and the rate of blood flow in the liver on the clearance of drugs (review);Pharmaceutical Chemistry Journal;1993-11
5. Influence of Albumin on the Distribution and Elimination Kinetics of Diclofenac in the Isolated Perfused Rat Liver: Analysis by the Impulse-Response Technique and the Dispersion Model;Journal of Pharmaceutical Sciences;1993-04
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