Pharmacokinetic modeling of the elimination of drugs by the liver. II. Influence of the localization and activity of metabolizing enzymes and the rate of blood flow in the liver on the clearance of drugs (review)-Reference-Cited by-同舟云学术

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Pharmacokinetic modeling of the elimination of drugs by the liver. II. Influence of the localization and activity of metabolizing enzymes and the rate of blood flow in the liver on the clearance of drugs (review)

Published:1993-11 Issue:11-12 Volume:26 Page:813-819
ISSN:0091-150X
Container-title:Pharmaceutical Chemistry Journal
language:en
Short-container-title:Pharm Chem J

Author:

Lutsevich A. N.,Kirichuk V. F.

Publisher

Springer Science and Business Media LLC

Subject

Drug Discovery,Pharmacology

Link

https://link.springer.com/content/pdf/10.1007/BF00767651.pdf

Reference88 articles.

1. P. V. Gulak, A. M. Dudchenko, V. V. Zaitsev, et al., The Hepatocyte: Functional-Metabolic Properties [in Russian], Moscow (1985).

2. L. Bass, S. Keiding, K. Winkler, and N. Tygstrup, J. Theor. Biol.,61, 393–409 (1976).

3. L. Bass, J. Theor. Biol.,86, 365–376 (1980).

4. L. Bass, Am. J. Physiol.,244, G583-G589 (1983).

5. L. Bass, Circulation,72, Suppl. IV, 47–52 (1985).

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