Activation of signal transducer and activator of transcription 3 (Stat3) pathway in osteosarcoma cells and overexpression of phosphorylated-Stat3 correlates with poor prognosis

Author:

Ryu Keinosuke,Choy Edwin,Yang Cao,Susa Michiro,Hornicek Francis J.,Mankin Henry,Duan Zhenfeng

Publisher

Wiley

Subject

Orthopedics and Sports Medicine

Reference46 articles.

1. Common musculoskeletal tumors of childhood and adolescence;Arndt;N Engl J Med,1999

2. Osteosarcoma incidence and survival rates from 1973 to 2004: data from the Surveillance, Epidemiology, and End Results Program;Mirabello;Cancer,2009

3. Stat3 as an oncogene;Bromberg;Cell,1999

4. Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention;Buettner;Clin Cancer Res,2002

5. Indirubin derivatives inhibit Stat3 signaling and induce apoptosis in human cancer cells;Nam;Proc Natl Acad Sci USA,2005

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