Point estimation andp-values in phase II adaptive two-stage designs with a binary endpoint
Author:
Affiliation:
1. Institute for Medical Biometry and Informatics; University of Heidelberg; Marsilius Arkaden, Im Neuenheimer Feld 130.3 Heidelberg 69120 Germany
Funder
Deutsche Forschungsgemeinschaft
Publisher
Wiley
Subject
Statistics and Probability,Epidemiology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/sim.7200/fullpdf
Reference18 articles.
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2. Adaptive two-stage designs for single-arm phase IIA cancer clinical trial;Lin;Biometrics,2004
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4. Optimal adaptive two-stage designs for phase II cancer clinical trials;Englert;Biometrical Journal,2013
5. Optimal adaptive two-stage designs for early phase-II clinical trials;Shan;Statistics in Medicine,2016
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