Efficacy and safety of two administration modes of an intra-detrusor injection of 750 units dysport® (abobotulinumtoxinA) in patients suffering from refractory neurogenic detrusor overactivity (NDO): A randomised placebo-controlled phase IIa study

Author:

Denys Pierre1,Del Popolo Giulio2,Amarenco Gerard3,Karsenty Gilles4,Le Berre Philippe5,Padrazzi Bruno5,Picaut Philippe5,

Affiliation:

1. Department of Physical Medicine and Rehabilitation; Hôpital Raymond-Poincaré AP-HP; Garches France

2. Department of Neurourology; Careggi University Hospital; Florence Italy

3. Department of Neurourology; Hôpital Tenon; Paris France

4. Department of Urology; Hôpital de la Conception; Marseille France

5. Ipsen Innovation; Les Ulis France

Funder

Ipsen Pharma

Publisher

Wiley

Subject

Urology,Neurology (clinical)

Reference20 articles.

1. The neural control of micturition;Fowler;Nat Rev Neurosci,2008

2. Diagnosis and therapy for neurogenic bladder dysfunctions in multiple sclerosis patients;Del Popolo;Neurol Sci,2008

3. Blok B Pannek J Castra Diaz D EEAU guidelines on neuro-urology 2015 http://uroweb.org/wp-content/uploads/EAU-Guidelines-Neuro-Urology-2015-v2.pdf 2015

4. Muscarinic receptor antagonists in the treatment of overactive bladder;Chapple;Urology,2000

5. Efficacy and safety of onabotulinumtoxinA in patients with urinary incontinence due to neurogenic detrusor overactivity: A randomized, double-blind, placebo-controlled trial;Cruz;Eur Urol,2011

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