Evaluation of the Pharmacokinetic Interaction Between the β3-Adrenoceptor Agonist Mirabegron and the Muscarinic Receptor Antagonist Solifenacin In Healthy Subjects

Author:

Krauwinkel Walter J. J.1,Kerbusch Virginie M. M.2,Meijer John1,Tretter Reiner1,Strabach Gregory3,Van Gelderen E. Marcel1

Affiliation:

1. Astellas Pharma Europe BV; Leiderdorp; The Netherlands

2. PharmAspire Consulting; Wijchen; The Netherlands

3. Société Générale de Surveillance (SGS); Paris; France

Publisher

Wiley

Subject

Pharmacology (medical),Pharmaceutical Science

Reference21 articles.

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2. Reviewing the ICS 2002C terminology report: the ongoing debate;Abrams;Neurourol Urodyn.,2009

3. An overview of the clinical use of antimuscarinics in the treatment of overactive bladder;Athanasopoulos;Adv Urol.,2011

4. β3-adrenoceptors in urinary bladder;Yamaguchi;Neurourol Urodyn.,2007

5. In vitro inhibition and induction of human cytochrome P450 enzymes by mirabegron (YM178), a potent and selective ß3-adrenoceptor agonist;Takusagawa;Xenobiotica.,2012

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