Physiologically Based Pharmacokinetic Modeling Suggests Limited Drug‐Drug Interaction for Fesoterodine When Coadministered With Mirabegron
Author:
Affiliation:
1. Medicine Design — Department of Pharmacokinetics, Dynamics, and MetabolismPfizer Inc. Groton CT USA
2. Pfizer Japan Inc. Tokyo Japan
3. Pfizer Inc. New York NY USA
Funder
Pfizer
Publisher
Wiley
Subject
Pharmacology (medical),Pharmacology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/jcph.1438
Reference29 articles.
1. TOVIAZ (fesoterodine) prescribing information.New York NY:Pfizer Labs; January 2014.
2. MYRBETRIQ (mirabegron) prescribing information.Northbrook IL:Astellas Pharma US Inc.; August 2016.
3. Fesoterodine for overactive bladder: A review of the literature
4. Role of Cytochrome P450 Isoenzymes 3A and 2D6 in the In Vivo Metabolism of Mirabegron, a β3-Adrenoceptor Agonist
5. The effect of mirabegron, a potent and selective β3-adrenoceptor agonist, on the pharmacokinetics of CYP2D6 substrates desipramine and metoprolol
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