Affiliation:
1. Department of Chemistry Chonnam National University Gwangju 61186 Republic of Korea
Abstract
AbstractThe Friedel‐Crafts acylation reaction between activated amides and arenes was carried out by employing [Pd(cinnamyl)Cl]2 and Cu(OTf)2 as catalysts. A range of N‐phenyl‐N‐tosylbenzamides, which were substituted at the phenyl ring of the benzamide moiety, underwent reaction with various arenes, such as mesitylene, toluene, anisole, 4‐tert‐butylbenzene, o‐xylene, m‐xylene, and p‐xylene, affording the corresponding diaryl ketones with yields ranging from 49% to 89%.
Funder
Korea Basic Science Institute
Subject
Organic Chemistry,Catalysis