Affiliation:
1. School of Chemical Engineering Yeungnam University Gyeongsan 38541 Republic of Korea.
2. Department of Chemistry Indian Institute of Science Education and Research (IISER) Tirupati 517507 India
Abstract
AbstractA substrate‐controlled [4+1] annulation of sulfoxonium ylides with maleimides via Rh(III)‐catalyzed C−H bond activation is developed. The reaction of sulfoxonium ylides with 2‐methyl‐N‐arylmaleimides in the presence of AgNTf2 diastereoselectively provides diversely functionalized indanonylpyrroline‐2,5‐dione derivatives. Furthermore, in the presence of AgBF4, the subsequent reaction with maleimides leads to biologically intriguing various spiroindanonylpyrroline‐2,5‐diones. This methodology offers a broad substrate scope, good functional group tolerance, and diastereoselectivity.