Combined treatment, based on lysomustine administration with mesenchymal stem cells expressing cytosine deaminase therapy, leads to pronounced murine Lewis lung carcinoma growth inhibition
Author:
Affiliation:
1. Pushchino State Institute of Natural Sciences; Pushchino Russia
2. Engelhardt Institute of Molecular Biology RAS; Moscow Russia
3. N. N. Blokhin Cancer Research Center; Russia
Publisher
Wiley
Subject
Genetics(clinical),Drug Discovery,Genetics,Molecular Biology,Molecular Medicine
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/jgm.2894/fullpdf
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2. Neural stem cell-mediated enzyme-prodrug therapy for glioma: preclinical studies;Aboody;Sci Transl Med,2013
3. Cytosine deaminase expressing human mesenchymal stem cells mediated tumour regression in melanoma bearing mice;Kucerova;J Gene Med,2008
4. Long-term efficiency of mesenchymal stromal cell-mediated CD-MSC/5FC therapy in human melanoma xenograft model;Kucerova;Gene Ther,2014
5. Adipose tissue-derived human mesenchymal stem cells mediated prodrug cancer gene therapy;Kucerova;Cancer Res,2007
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