Development of a mathematical model for animal cell culture without pH control and its application for evaluation of clone screening outcomes in shake flask culture

Author:

Gadgil Mugdha1

Affiliation:

1. Chemical Engineering and Process Development; CSIR-National Chemical Laboratory; Pune India 411008

Funder

Department of Science and Technology, Ministry of Science and Technology

Council of Scientific and Industrial Research

Publisher

Wiley

Subject

Inorganic Chemistry,Organic Chemistry,Pollution,Waste Management and Disposal,Fuel Technology,Renewable Energy, Sustainability and the Environment,General Chemical Engineering,Biotechnology

Reference49 articles.

1. Logistic equations effectively model Mammalian cell batch and fed-batch kinetics by logically constraining the fit;Goudar;Biotechnol Prog,2005

2. Systems biotechnology of mammalian cell factories;O'Callaghan;Brief Funct Genomic Proteomic,2008

3. Modelling hybridoma cell growth and metabolism - a comparison of selected models and data;Pörtner;J Biotechnol,1996

4. Modeling kinetics of a large-scale fed-batch CHO cell culture by Markov chain Monte Carlo method;Xing;Biotechnol Prog,2010

5. Mathematical modeling and analysis of monoclonal antibody production by hybridoma cells;Zeng;Biotechnol Bioeng,1996

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