In vitro characterisation of solid drug nanoparticle compositions of efavirenz in a brain endothelium cell line

Author:

Curley Paul1ORCID,Giardiello Marco2,Liptrott Neill J.13ORCID,Dickens David1,Moss Darren M.1,Hobson James J.2,Savage Alison C.2,McDonald Tom O.2,Siccardi Marco1,Rannard Steve23,Owen Andrew13

Affiliation:

1. Molecular and Clinical Pharmacology, Institute of Translational Medicine; University of Liverpool; Liverpool UK

2. Department of Chemistry; University of Liverpool; Crown Street Liverpool UK

3. European Nanomedicine Characterisation Laboratory, Molecular and Clinical Pharmacology, Institute of Translational Medicine; University of Liverpool; Liverpool UK

Publisher

Wiley

Reference43 articles.

1. Efavirenz;Adkins;Drugs,1998

2. Advances in brain targeting and drug delivery of anti-HIV therapeutic agents;Al-Ghananeem;Expert Opin Drug Deliv,2013

3. Misoprostol-induced fever and genetic polymorphisms in drug transporters SLCO1B1 and ABCC4 in women of Latin American and European ancestry;Alfirevic;Pharmacogenomics,2015

4. Dynasore, a dynamin inhibitor, inhibits Trypanosoma cruzi entry into peritoneal macrophages;E. S.;PLoS One,2010

5. Efavirenz concentrations in CSF exceed IC50 for wild-type HIV;Best;J Antimicrob Chemother,2011

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