Relationship between the plasma concentration of paliperidone and the clinical and drug-induced extrapyramidal symptoms in elderly patients with schizophrenia

Author:

Suzuki Hidenobu1,Gen Keishi2,Otomo Masahiro2,Inoue Yuichi3,Hibino Hiroyuki4,Mikami Ayako5,Matsumoto Hideo6,Mikami Katsunaka6

Affiliation:

1. Department of Psychiatry; Suzuki Clinic; Tokyo Japan

2. Department of Psychiatry; Seimo Hospital; Gunma Japan

3. Shakomae Kokorono Clinic; Tokyo Japan

4. Department of Psychiatry; Fukui Kinen Hospital; Kanagawa Japan

5. Department of Clinical Pharmacology; Tokai University School of Medicine; Kanagawa Japan

6. Department of Psychiatry; Tokai University School of Medicine; Kanagawa Japan

Publisher

Wiley

Subject

Pharmacology (medical),Psychiatry and Mental health,Clinical Neurology,Neurology

Reference24 articles.

1. Dose-finding study of paliperidone ER based on striatal and extrastriatal dopamine D2 receptor occupancy inpatients with schizophrenia;Arakawa;Psychopharmacol (Ber1),2008

2. A rating scale for drug induced akathisia;Barnes;Br J Psychiatry,1989

3. Olanzapine: a systematic review and meta-regression of the relationships between dose, plasma concentration, receptor occupancy, and response;Bishara;J Clin Psychopharmacol,2013

4. The influence of hepatic impairment on the pharmacokinetics of paliperidone;Boom;Int J Clin Pharmacol Ther,2009

5. Drug-drug interactions associated with second-generation antipsychotics: considerations for clinicians and patients;Conley;Psychopharmacol Bull,2007

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