GPR55 receptor antagonist decreases glycolytic activity in PANC-1 pancreatic cancer cell line and tumor xenografts

Author:

Bernier Michel1,Catazaro Jonathan2,Singh Nagendra S.3,Wnorowski Artur4,Boguszewska-Czubara Anna5,Jozwiak Krzysztof4,Powers Robert2,Wainer Irving W.36ORCID

Affiliation:

1. Translational Gerontology Branch, Intramural Research Program of the National Institute on Aging, National Institutes of Health; Baltimore MD 21224

2. Department of Chemistry; University of Nebraska-Lincoln; Lincoln NE 68588-0304

3. Laboratory of Clinical Investigation; Intramural Research Program of the National Institute on Aging, National Institutes of Health; Baltimore MD 21224

4. Department of Biopharmacy; Medical University of Lublin; Lublin 20-093 Poland

5. Department of Medical Chemistry; Medical University of Lublin; Lublin 20-093 Poland

6. Mitchell Woods Pharmaceuticals; Shelton CT 06484

Funder

Intramural Research Program of the National Institute on Aging at NIH, from the National Institutes of Health

Nebraska Center for Integrated Biomolecular Communication Systems Biology Core, NIH National Institutes of General Medical Sciences

National Institutes of Health

NIH Public Access Policy

Publisher

Wiley

Subject

Cancer Research,Oncology

Reference60 articles.

1. On the origin of cancer cells;Warburg;Science,1956

2. Glycolysis inhibition for anticancer treatment;Pelicano;Oncogene,2006

3. Tumor glycolysis as a target for cancer therapy: progress and prospects;Ganapathy-Kanniappan;Mol Cancer,2013

4. Targeting glucose metabolism for cancer therapy;Hamanaka;J Exp Med.,2012

5. Metabolic changes in cancer: beyond the Warburg effect;Wu;Acta Biochim Biophys Sin (Shanghai).,2013

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