Combined Simulation and Mutation Studies to Elucidate Selectivity of Unsubstituted Amphetamine-like Cathinones at the Dopamine Transporter-Reference-Cited by-同舟云学术

Combined Simulation and Mutation Studies to Elucidate Selectivity of Unsubstituted Amphetamine-like Cathinones at the Dopamine Transporter

Published:2016-11-08 Issue:5-6 Volume:36 Page:1600094
ISSN:1868-1743
Container-title:Molecular Informatics
language:en
Short-container-title:Mol. Inf.

Author:

Seddik Amir¹,Geerke Daan P.²,Stockner Thomas³,Holy Marion³,Kudlacek Oliver³,Cozzi Nicholas V.⁴,Ruoho Arnold E.⁵,Sitte Harald H.³,Ecker Gerhard F.¹

Affiliation:

1. University of Vienna; Department of Pharmaceutical Chemistry; Althanstrasse 14 1090 Vienna Austria

2. AIMMS Division of Molecular Toxicology; Department of Chemistry and Pharmaceutical Sciences; VU University; De Boelelaan 1083 1081 HV Amsterdam the Netherlands

3. Medical University of Vienna; Institute of Pharmacology; Center for Physiology and Pharmacology; Währingerstrasse 13a 1090 Vienna Austria

4. Department of Cell and Regenerative Biology; University of Wisconsin School of Medicine and Public Health; 1300 University Avenue Madison WI 53706

5. Department of Neuroscience; University of Wisconsin School of Medicine and Public Health; 1300 University Avenue Madison WI 53706

Funder

Austrian Science Fund

Publisher

Wiley

Subject

Organic Chemistry,Computer Science Applications,Drug Discovery,Molecular Medicine,Structural Biology

Reference36 articles.

1. SEROTONIN (5-HT) RECEPTOR, 5-HT TRANSPORTER AND G PROTEIN-EFFECTOR EXPRESSION: IMPLICATIONS FOR DEPRESSION

2. Association of Anxiety-Related Traits with a Polymorphism in the Serotonin Transporter Gene Regulatory Region

3. Enhanced Dopamine Transporter Density in Psychotropic-Naive Patients With Obsessive-Compulsive Disorder Shown by [123I]β-CIT SPECT

4. Evidence that variation at the serotonin transporter gene influences susceptibility to attention deficit hyperactivity disorder (ADHD): analysis and pooled analysis

5. Dopamine-transporter density in patients with ADHD

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