Cullin3/KCTD5 induces monoubiquitination of ΔNp63α and impairs its activity

Author:

He Hanbing1,Peng Yougong2,Fan Shijie1,Chen Yonglong1,Zheng Xuan1,Li Chenghua1

Affiliation:

1. Center of Growth, Metabolism and Aging; Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education; College of Life Sciences; Sichuan University; Chengdu China

2. Department of General Surgery; The Second People's Hospital of Jingmen; China

Funder

National Natural Science Foundation of China

Department of Science and Technology of Sichuan Province

Publisher

Wiley

Subject

Cell Biology,Genetics,Molecular Biology,Biochemistry,Structural Biology,Biophysics

Reference26 articles.

1. A double dealing tale of p63: an oncogene or a tumor suppressor;Chen;Cell Mol Life Sci,2018

2. p53/p63/p73 isoforms: an orchestra of isoforms to harmonise cell differentiation and response to stress;Murray-Zmijewski;Cell Death Differ,2006

3. DeltaNp63alpha regulates Erk signaling via MKP3 to inhibit cancer metastasis;Bergholz;Oncogene,2014

4. Regulation of p63 protein stability via ubiquitin-proteasome pathway;Li;Biomed Res Int,2014

5. HECT and RING finger families of E3 ubiquitin ligases at a glance;Metzger;J Cell Sci,2012

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