Interface‐based design of the favipiravir‐binding site in SARS‐CoV‐2 RNA‐dependent RNA polymerase reveals mutations conferring resistance to chain termination-Reference-Cited by-同舟云学术

Interface‐based design of the favipiravir‐binding site in SARS‐CoV‐2 RNA‐dependent RNA polymerase reveals mutations conferring resistance to chain termination

Published:2021-09 Issue:18 Volume:595 Page:2366-2382
ISSN:0014-5793
Container-title:FEBS Letters
language:en
Short-container-title:FEBS Lett

Author:

Padhi Aditya K.¹,Dandapat Jagneshwar²³^ORCID,Saudagar Prakash⁴^ORCID,Uversky Vladimir N.⁵^ORCID,Tripathi Timir⁶^ORCID

Affiliation:

1. Laboratory for Structural Bioinformatics Center for Biosystems Dynamics Research RIKEN Yokohama Japan

2. Centre of Excellence in Integrated Omics and Computational Biology Utkal University Bhubaneswar India

3. Post Graduate Department of Biotechnology Utkal University Bhubaneswar India

4. Department of Biotechnology National Institute of Technology‐Warangal India

5. Department of Molecular Medicine and Byrd Alzheimer's Research Institute Morsani College of Medicine University of South Florida Tampa FL USA

6. Molecular and Structural Biophysics Laboratory Department of Biochemistry North‐Eastern Hill University Shillong India

Publisher

Wiley

Subject

Cell Biology,Genetics,Molecular Biology,Biochemistry,Structural Biology,Biophysics

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/1873-3468.14182

Reference52 articles.

1. Structure of the RNA-dependent RNA polymerase from COVID-19 virus

2. Structure of replicating SARS-CoV-2 polymerase

3. Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir

4. A new coronavirus associated with human respiratory disease in China

5. Favipiravir (T-705), a novel viral RNA polymerase inhibitor

Cited by 24 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. SARS-CoV-2 Resistance to Small Molecule Inhibitors;Current Clinical Microbiology Reports;2024-06-24

2. Antivirals for Broader Coverage against Human Coronaviruses;Viruses;2024-01-20

3. Interface design of SARS-CoV-2 symmetrical nsp7 dimer and machine learning-guided nsp7 sequence prediction reveals physicochemical properties and hotspots for nsp7 stability, adaptation, and therapeutic design;Physical Chemistry Chemical Physics;2024

4. Uncovering the secrets of resistance: An introduction to computational methods in infectious disease research;Advances in Protein Chemistry and Structural Biology;2024

5. Interface‐Guided Computational Protein Design Reveals Bebtelovimab‐Resistance Mutations in SARS‐CoV‐2 RBD: Correlation with Global Viral Genomes and Bebtelovimab‐Escape Mutations;ChemistrySelect;2023-12-11