MRP1 mediates folate transport and antifolate sensitivity inPlasmodium falciparum

Author:

Rijpma Sanna R.1,van der Velden Maarten1,Bilos Albert1,Jansen Robert S.2,Mahakena Sunny2,Russel Frans G. M.1,Sauerwein Robert W.3,van de Wetering Koen2,Koenderink Jan B.1

Affiliation:

1. Department of Pharmacology and Toxicology; Radboud University Medical Center; Nijmegen The Netherlands

2. Division of Molecular Oncology; Netherlands Cancer Institute; Amsterdam The Netherlands

3. Department of Medical Microbiology; Radboud University Medical Center; Nijmegen The Netherlands

Funder

Radboud Universitair Medisch Centrum

Publisher

Wiley

Subject

Cell Biology,Genetics,Molecular Biology,Biochemistry,Structural Biology,Biophysics

Reference57 articles.

1. The ABCs of multidrug resistance in malaria;Koenderink;Trends Parasitol,2009

2. Mammalian ABC transporters in health and disease;Borst;Annu Rev Biochem,2002

3. Localization of the ATP-binding cassette (ABC) transport proteins PfMRP1, PfMRP2, and PfMDR5 at the Plasmodium falciparum plasma membrane;Kavishe;Malar J,2009

4. Plasmodium falciparum multidrug resistance protein (MRP) gene expression under chloroquine and mefloquine challenge;Nogueira;J Cell Anim Biol,2008

5. Polymorphism in PfMRP1 (Plasmodium falciparum multidrug resistance protein 1) amino acid 1466 associated with resistance to sulfadoxine-pyrimethamine treatment;Dahlstrom;Antimicrob Agents Chemother,2009

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