Co-delivery of platelet-derived growth factor (PDGF-BB) and bone morphogenic protein (BMP-2) coated onto heparinized titanium for improving osteoblast function and osteointegration

Author:

Kim Sung Eun1,Yun Young-Pil1,Lee Jae Yong1,Shim June-Sung2,Park Kyeongsoon3,Huh Jung-Bo24

Affiliation:

1. Department of Orthopaedic Surgery and Rare Diseases Institute; Korea University Medical Centre, Guro Hospital; 80 Guro-dong Guro-gu Seoul 152-703 Korea

2. Department of Prosthodontics, College of Dentistry; Younsei University; 134 Sinchon-dong Seodaemun-gu Seoul 120-749 Korea

3. Division of Biological Imaging, Chuncheon Centre; Korea Basic Science Institute; 192-1 Hyoja 2-dong Chuncheon Gangwon-do 200-701 Korea

4. Department of Prosthodontics, School of Dentistry; Pusan National University; Yang San 626-787 Korea

Funder

Ministry of Education, Science and Technology

KBSI

Korea Healthcare Technology R&D Project, Ministry of Health and Welfare, Republic of Korea

Publisher

Wiley

Subject

Biomedical Engineering,Biomaterials,Medicine (miscellaneous)

Reference40 articles.

1. Platelet-derived growth factor expression in normally healing human fractures;Andrew;Bone,1995

2. Guided tissue regeneration for implants placed into extraction sockets: a study in dogs;Becker;J Periodontol,1991

3. Regulation of fracture repair by growth factors;Bolander;Proc Soc Exp Biol Med,1992

4. Relative binding and biochemical effects of heterodimeric and homodimeric isoforms of platelet-derived growth factor in osteoblast-enriched cultures from fetal rat bone;Centrella;J Cell Physiol,1991

5. Effect of PDGF-BB and β-tricalcium phosphate (β-TCP) on bone formation around dental implants: a pilot study in sheep;Choo;Clin Oral Implants Res,2011

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