An alternate diafiltration strategy to mitigate protein precipitation for low solubility proteins
Author:
Affiliation:
1. Purification Process Development; Amgen, Inc.; Seattle WA
2. EMD Millipore; Playa del Rey CA
Publisher
Wiley
Subject
Biotechnology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/btpr.1872/fullpdf
Reference19 articles.
1. Membrane ultrafiltration: The diafiltration technique and its application to microsolute exchange and binding phenomena;Blatt;Anal Biochem,1968
2. Optimization of solute separation by diafiltration;Ng;Sep Sci Technol,1976
3. Ultrafiltration of immune serum globulin and human serum albumin: Regression analysis studies;Mitra;Sep Sci Technol,1978
4. Shear effects on enzymes;Charm;Enzyme Microb Technol,1981
5. Studies of the effects of shear on globular proteins: Extension to high shear fields and pumps;Virkar;Biotechnol Bioeng,1981
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