Ultrafiltration of highly concentrated antibody solutions: Experiments and modeling for the effects of module and buffer conditions
Author:
Affiliation:
1. Dept. of Chemical Engineering; the Pennsylvania State University; University Park PA 16802
2. Amgen, Inc.; Thousand Oaks CA 91320
Publisher
Wiley
Subject
Biotechnology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/btpr.2252/fullpdf
Reference16 articles.
1. Bioprocess membrane technology;Reis;J Membr Sci.,2007
2. Challenges in the development of high protein concentration formulations;Shire;J Pharm Sci.,2004
3. Ultrafiltration concentration of monoclonal antibody solutions: development of an optimized method minimizing aggregation;Rosenberg;J Membr Sci.,2009
4. Comparison of different protein concentration techniques within formulation development;Eppler;Int J Pharm.,2011
5. The osmotic pressure of highly concentrated monoclonal antibody solutions: effect of solution conditions;Binabaji;Biotechnol Bioeng.,2014
Cited by 34 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Deterministic mathematical modeling, sensitivity analysis, and dynamic optimization of cross-flow ultrafiltration systems for concentration of monoclonal antibody solutions;Computers & Chemical Engineering;2024-08
2. Stability of Protein Pharmaceuticals: Recent Advances;Pharmaceutical Research;2024-06-27
3. A model-based performance analysis of integrated chromatography-ultrafilter separation systems for monoclonal antibody (mAb) manufacturing;Biochemical Engineering Journal;2024-06
4. Evaluation of various membranes at different fluxes to enable large‐volume single‐use perfusion bioreactors;Biotechnology and Bioengineering;2024-05-04
5. Effect of inner diameter, filter length, and pore size on hollow fiber filter fouling during perfusion cell culture;Biotechnology Progress;2024-02-11
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3