Normalized Testosterone Glucuronide as a Potential Urinary Biomarker for Highly Variable UGT2B17 in Children 7

Normalized Testosterone Glucuronide as a Potential Urinary Biomarker for Highly Variable UGT2B17 in Children 7–18 Years

Published:2020-02-12 Issue:5 Volume:107 Page:1149-1158
ISSN:0009-9236
Container-title:Clinical Pharmacology & Therapeutics
language:en
Short-container-title:Clin. Pharmacol. Ther.

Author:

Zhang Haeyoung¹,Basit Abdul¹,Wolford Chris¹,Chen Kuan‐Fu¹,Gaedigk Andrea²,Lin Yvonne S.¹,Leeder J. Steven²,Prasad Bhagwat¹

Affiliation:

1. Department of Pharmaceutics University of Washington Seattle Washington USA

2. Division of Clinical Pharmacology, Toxicology, and Therapeutic Innovation Department of Pediatrics, Children's Mercy Kansas City University of Missouri‐Kansas City Kansas City Missouri USA

Funder

National Institutes of Health

University of Washington

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cpt.1764

Reference49 articles.

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4. Hepatic Abundance and Activity of Androgen- and Drug-Metabolizing Enzyme UGT2B17 Are Associated with Genotype, Age, and Sex

5. Characterization of UDP-glucuronosyltransferases active on steroid hormones

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