Hepatic Abundance and Activity of Androgen- and Drug-Metabolizing Enzyme UGT2B17 Are Associated with Genotype, Age, and Sex-Reference-Cited by-同舟云学术

Hepatic Abundance and Activity of Androgen- and Drug-Metabolizing Enzyme UGT2B17 Are Associated with Genotype, Age, and Sex

Published:2018-03-30 Issue:6 Volume:46 Page:888-896
ISSN:0090-9556
Container-title:Drug Metabolism and Disposition
language:en
Short-container-title:Drug Metab Dispos

Author:

Bhatt Deepak Kumar,Basit Abdul,Zhang Haeyoung,Gaedigk Andrea,Lee Seung-been,Claw Katrina G.,Mehrotra Aanchal,Chaudhry Amarjit Singh,Pearce Robin E.,Gaedigk Roger,Broeckel Ulrich,Thornton Timothy A.,Nickerson Deborah A.,Schuetz Erin G.,Amory John K.,Leeder J. Steven,Prasad Bhagwat

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmaceutical Science,Pharmacology

Reference49 articles.

1. The effect of copy number variation in the phase II detoxification genesUGT2B17andUGT2B28on colorectal cancer risk

2. Androgen receptor mediates the expression of UDP-glucuronosyltransferase 2 B15 and B17 genes

3. Inactivation of androgens by UDP-glucuronosyltransferases in the human prostate

4. Isolation and Characterization of a Novel cDNA Encoding a Human UDP-Glucuronosyltransferase Active on C19 Steroids

5. Age-dependent Protein Abundance of Cytosolic Alcohol and Aldehyde Dehydrogenases in Human Liver

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