Sorafenib use in hepatocellular carcinoma: More questions than answers
Author:
Affiliation:
1. Department of Internal Medicine; Memorial Sloan-Kettering Cancer Center; New York NY
2. Department of Internal Medicine; Weill Cornell Medical College; New York NY
Publisher
Wiley
Subject
Hepatology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/hep.27044/fullpdf
Reference25 articles.
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3. RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth;Hatzivassiliou;Nature,2010
4. Cyclic AMP/PKA-dependent paradoxical activation of Raf/MEK/ERK signaling in polycystin-2 defective mice treated with sorafenib;Spirli;Hepatology,2012
5. Phase I clinical and pharmacokinetic study of the Novel Raf kinase and vascular endothelial growth factor receptor inhibitor BAY 43-9006 in patients with advanced refractory solid tumors;Strumberg;J Clin Oncol,2005
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