An efficient synthesis of 6‐benzyl‐2‐arylthieno[2,3‐ d ]pyrimidin‐4( 3 H )‐ones catalyzed by HCl involving a Friedel‐Crafts alkylation reaction
Author:
Affiliation:
1. School of Chemistry and Materials Science, Jiangsu Key Laboratory of Green Synthesis for Functional Materials Jiangsu Normal University Xuzhou P. R. China
Publisher
Wiley
Subject
Organic Chemistry
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/jhet.4107
Reference47 articles.
1. Design and synthesis of alkyl substituted pyridino[2,3-D]pyrimidine compounds as PI3Kα/mTOR dual inhibitors with improved pharmacokinetic properties and potent in vivo antitumor activity
2. Design, Synthesis, and Biological Evaluation of Pyrimido[4,5-d]pyrimidine-2,4(1H,3H)-diones as Potent and Selective Epidermal Growth Factor Receptor (EGFR) Inhibitors against L858R/T790M Resistance Mutation
3. Novel pyrimidinic selenourea induces DNA damage, cell cycle arrest, and apoptosis in human breast carcinoma
4. Synthesis, characterization and cytotoxicity studies of 1,2,3-triazoles and 1,2,4-triazolo [1,5-a] pyrimidines in human breast cancer cells
5. Low-dose all-trans retinoic acid enhances cytotoxicity of cisplatin and 5-fluorouracil on CD44+ cancer stem cells
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