Targeted Protein Degradation: Design Considerations for PROTAC Development-Reference-Cited by-同舟云学术

Targeted Protein Degradation: Design Considerations for PROTAC Development

Published:2022-12 Issue:12 Volume:2 Page:
ISSN:2691-1299
Container-title:Current Protocols
language:en
Short-container-title:Current Protocols

Author:

Tran Nathan L.¹,Leconte Georges A.¹,Ferguson Fleur M.¹²

Affiliation:

1. Department of Chemistry and Biochemistry University of California, La Jolla San Diego California USA

2. Skaggs School of Pharmacy and Pharmaceutical Sciences University of California, La Jolla San Diego California USA

Publisher

Wiley

Subject

Medical Laboratory Technology,Health Informatics,General Pharmacology, Toxicology and Pharmaceutics,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Neuroscience

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cpz1.611

Reference56 articles.

1. Rationalizing PROTAC-Mediated Ternary Complex Formation Using Rosetta

2. Unraveling the Role of Linker Design in Proteolysis Targeting Chimeras

3. Lessons in PROTAC Design from Selective Degradation with a Promiscuous Warhead

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